University of Wisconsin–Madison Medical College of Wisconsin

Cranial Nerve VI Palsy Secondary to Herpes Zoster Ophthalmicus: A Case Report and Literature Review

Clara V. Kuranz, BS; Jennifer Larson, MD

WMJ. 2024;123(3):222-224.

Download full-text pdf

ABSTRACT

Introduction: In this report, we describe a rare case of a cranial nerve VI palsy secondary to herpes zoster infection with polyneuropathic involvement.

Case Presentation: An 82-year-old male was seen by ophthalmology for acute onset of double vision. Fourteen days before presenting, he was diagnosed with herpes zoster ophthalmicus. He was suspected to have zoster polyneuropathy also involving cranial nerve IX and X given a sore throat that began prior to the characteristic trigeminal dermatomal rash. He was diagnosed with cranial nerve VI palsy secondary to herpes zoster infection.

Discussion: Ophthalmic complications of herpes zoster ophthalmicus are many; however, extraocular nerve palsies secondary to herpes zoster infection and zoster polyneuropathy are documented infrequently in the literature.

Conclusions: Extraocular muscle palsies are a rare complication of herpes zoster infection. This case reviews the most current literature surrounding this condition and discusses the significance of polyneuropathic involvement in varicella zoster virus reactivation.


Author Affiliations: University of Wisconsin School of Medicine and Public Health (UWSMPH), Madison, Wisconsin (Kuranz); Department of Ophthalmology and Visual Sciences, UWSMPH, Madison, Wisconsin (Larson).
Corresponding Author: Jennifer Larson, MD, Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, 2349 Deming Way, Suite 200; Middleton, WI 53562; phone 608.824.3937; email jciske@wisc.edu; ORCID ID 0000-0001-5205-1529
Acknowledgements: Consent to publish this case report was obtained from the patient.
Financial Disclosures: None declared.
Funding/Support: This work was supported in part by an unrestricted grant from Research to Prevent Blindness, Inc to the UW-Madison Department of Ophthalmology and Visual Sciences.
Share WMJ