University of Wisconsin–Madison Medical College of Wisconsin

Pharmacotherapy Update

 

It’s challenging to keep informed of new developments in medications and their uses. WMJ’s Pharmacotherapy Update aims to provide detailed information about current, cutting-edge topics in the pharmacy world.

Read  more

Pharmacotherapy Update 3: Paxlovid (nirmatrelvir/ritonavir)

Paxlovid was authorized for emergency use on December 22, 2021, by the US Food and Drug Administration (FDA) for treatment of mild-to-moderate COVID-19 in adults and pediatric patients (12 years of age and older weighing at least 40 kg) with positive results of direct SARS-CoV-2 viral testing and who are at high risk for progression to severe COVD-19, including hospitalization or death. Since it is not FDA-approved at this time, Paxlovid is considered an investigational drug.

Published online November 10, 2022. 

Pharmacotherapy Update 2: Fluvoxamine and COVID-19

The past few years have witnessed several clinical studies that investigated the potential benefits of fluvoxamine maleate in treating COVID-19 patients. In December 2021, David R. Boulware, MD, MPH, a physician and researcher at the University of Minnesota, requested an emergency use authorization (EUA) for the use of fluvoxamine for early treatment of COVID-19 outpatients to prevent their clinical deterioration.

Published online June 6, 2022. 

Pharmacotherapy Update 1: Aducanumab

Aducanumab was approved on June 7, 2021 by the US Food and Drug Administration (FDA) using the accelerated approval pathway. Under this approval category, a drug must be used for a serious condition that fills an unmet medical need. The outcomes in the study are based on surrogate endpoints thought to predict clinical benefit but are not themselves a measure of clinical benefit.

Published online April 2, 2022. 

 

Share WMJ