University of Wisconsin–Madison Medical College of Wisconsin

Volume 113, Issue 5

October 2014

Human Genome Sequencing: What to do with incidental findings when treatment isn’t available

In addition to its potential to provide findings of clinical benefit, whole genome sequencing also has the potential to identify incidental findings—some for which no treatment is available. A study in this issue of WMJ considers the debate around how and which findings should be returned to patients, as well as their desires for such results.

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TABLE OF CONTENTS

Editorial

Letter to the Editor
Paucity of Laboratory-confirmed Failures of High-dose Influenza Vaccine in an Elderly Population, 2012-2013
Marvin J. Bittner MD; John M. Horne, MD
WMJ. 2014;113(5):173.

In This Issue
Information Is Not Knowledge and Certainly Not Wisdom
John J. Frey, III, MD, WMJ Medical Editor
WMJ. 2014;113(5):177-178.

Original Research

Views of Nonmedical, Health System Professionals Regarding the Return of Whole Genome Sequencing Incidental Findings
Kimberly A. Strong, PhD; Kaija L. Zusevics, PhD, MPH; David P. Bick, MD; Regan Veith, MS
WMJ. 2014;113(5):179-184.

A One-to-One Mentoring Support Service for Breast Cancer Survivors
Amanda L. Amin, MD; Joan Neuner, MD; Elizabeth A. Duthie, PhD; Virginia R. Finn, JD; Amanda L. Kong, MD, MS
WMJ. 2014;113(5):185-189.

Identifying Opportunities to Improve Aspirin Utilization for the Primary Prevention of Cardiovascular Disease in a Regional Health Care System
Jeffrey J. VanWormer, PhD; Aaron W. Miller, PhD; Shereif H. Rezkalla, MD
WMJ. 2014;113(5):190-195.

Case Reports

Osmotic Demyelination Syndrome
Narendranath Epperla, MD; Jillian Landeck; Salah Sabbagh, MD
WMJ. 2014;113(5):197-198.

Daptomycin-Induced Acute Eosinophilic Pneumonia
Jayshil J. Patel, MD; Agith Antony, MD; Maria Herrera, MD; Randolph J. Lipchik, MD
WMJ. 2014;113(5):199-201.

Streptococcus Infection in a Newborn
Jessica Molinaro, BA; Gary Cohen, MD; Kris Saudek, MD
WMJ. 2014;113(5):202-203.

Your Profession

Looking Back…to 1915
A Method of Treating Common Colds
Harrington and Richardson in the Manual of Practical Hygiene
WMJ. 2014;113(5):175.

MetaStar Matters
MetaStar Shows Marked Improvements for Medicare Patients, Looks to Future
Jay A. Gold, MD, JD, MPH
WMJ. 2014;113(5):205.

Your Practice

Ask This One Question
W. Stancil Starnes, JD
WMJ. 2014;113(5):206-207.

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