University of Wisconsin–Madison Medical College of Wisconsin

Description of Kratom Exposure Events in Wisconsin as Reported to the Wisconsin Poison Center, January 1, 2010 to September 1, 2022

Peter DeJonge, PhD; David Gummin, MD; Nicholas Titelbaum, MD; Jonathan Meiman, MD

WMJ. 2023;122(3):187-190

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Background: Consumption of kratom (Mitragyna speciosa), an herbal substance, can result in adverse health effects. We characterized kratom-associated adverse events in Wisconsin to provide pertinent recommendations for clinicians and public health practitioners.

Methods: Using Wisconsin Poison Center data, we searched for and summarized all records associated with exposure to “kratom,” “electronic delivery device containing kratom,” or “mitragyna” from January 1, 2010, to September 1, 2022.

Results: Kratom-associated exposure calls to the Wisconsin Poison Center increased 3.75 times during 2016 – 2020. Among all 59 calls, 26 (44.1%) reported concomitant use of another substance, agitation was the most common symptom reported (n = 23, 39%), and 7 persons required critical care. Three unintentional ingestions were reported in children aged less than 2 years old.

Discussion: Kratom-associated exposure calls to the Wisconsin Poison Center generally have been increasing in frequency since 2011. Wisconsinites who choose to use kratom might benefit from education regarding health risks and safe storage practices to avoid unintentional pediatric exposure.

Author Affiliations: Epidemic Intelligence Service, Division of Scientific Education and Professional Development, US Centers for Disease Control and Prevention, Atlanta, Georgia (DeJonge); Wisconsin Department of Health Services, Madison, Wisconsin (DeJonge, Meiman); Wisconsin Poison Center, Milwaukee, Wisconsin (Gummin); Agency for Toxic Substances and Disease Registry, Atlanta, Georgia (Titelbaum).
Corresponding Author: Peter DeJonge, PhD, Wisconsin Department of Health Services, Bureau of Environmental and Occupational Health, Room 150, 1 W Wilson St, Madison, WI 53703; phone 608.698.4326; email; ORCID ID 0000-0001-6794-0636
Financial Disclosures: None declared.
Funding/Support: None declared.
Disclaimers: The findings and conclusions in this report are those of the author(s) and do not necessarily represent the views of the Centers for Disease Control and Prevention/the Agency for Toxic Substances and Disease Registry.
Acknowledgement: Dr Gummin is a member (uncompensated) of the Board of Directors America’s Poison Centers.
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