Olivia R. Newgaard, BA; Rajeev Chaudhry, MBBS, MPH; Jenny A. Schutte, RN; Richard Arndt, PharmD; Jennifer R. Rich, MPH; Andrew D. Calvin, MD, MPH; Richard D. Hanna, MD
Background: Amiodarone is the most effective and commonly used antiarrhythmic medication. Given its risk of toxicity, routine monitoring is recommended but is challenging to ensure in clinical practice.
Methods: We created an intelligent application, built within our electronic health record, that identified every living patient with an active outpatient prescription by a clinician in our health system. The application was designed to identify patients with lapses in recommended monitoring and facilitate scheduling of overdue testing.
Results: The percentage of patients with overdue monitoring tests decreased with use of the application, with greatest improvement in pulmonary function testing.
Discussion: Implementing a program to monitor and mitigate adverse reactions to amiodarone by using programable features of an electronic health record is feasible.