University of Wisconsin–Madison Medical College of Wisconsin

An Eye for an Eye, An Ear for an Ear: A Midwestern Case Report of Vogt-Koyanagi-Harada Disease

Neil Dixit, MD; Emily Koller, MD; Nicole Avendaño, MD; Pinky Jha, MD

WMJ. 2025;124(3):300-303.

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ABSTRACT

Introduction: Vogt-Koyanagi-Harada (VKH) disease is an autoimmune condition affecting both ocular and extraocular systems. This case highlights the need for research into the epidemiology and pathophysiology of VKH.

Case Presentation: A 23-year-old cisgender Hispanic female presented to our tertiary care center with severe headache, eye pain, vision changes, photophobia, hearing loss with tinnitus, phonophobia, nausea, vomiting, and vertigo. She was diagnosed with VKH disease.

Discussion: This report shares a case of VKH disease in the Midwestern United States. A 2023 Northwestern University study highlights the orphan nature of the disease; even with a small sample size, that study proved to be a larger cohort in studies of VKH.

Conclusions: This report contributes to the growing literature documenting VKH disease. Especially in diagnoses associated with certain racial groups, a broad differential diagnosis is essential, as delay in diagnosis may result in irreversible sequelae. Prompt coordination with colleagues may reduce subsequent morbidity and mortality.


Author Affiliations: Medical College of Wisconsin, Milwaukee, Wisconsin (Dixit, Koller, Avendaño, Jha).
Corresponding Author: Neil Dixit, email neildixi@med.umich.edu; ORCID ID 0009-0005-6580-7416
Financial Disclosures: None declared.
Funding/Support: None declared.
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