University of Wisconsin–Madison Medical College of Wisconsin

Renal Cell Carcinoma Presenting With Combined Cervical Lymphadenopathy and Cardiac Metastasis Without Inferior Vena Cava Involvement

Rana M. Usman, MD; Owais Yahya, MD; Hemnishil K. Marella, DO; Amit L. Jain, MD; Rahul Peravali, BS; Reshma Premkumar; Robert Bradsher, MD

WMJ. 2021;120(2):142-144.

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Renal cell cancer is the third most common urological malignancy following prostate and bladder malignancies. Cardiac metastases to the right side of the heart without inferior vena cava (IVC) involvement are exceedingly rare, with only a handful of cases described in the literature. Metastasis to the head and neck region is also rare, occurring in an estimated 1% of cases. Here we present a case of a patient with recurrent syncopal events secondary to renal cell carcinoma without IVC involvement, with metastases both to the right ventricle and cervical lymph nodes. To our knowledge, this is the first case that presents with both of these rare findings together and that highlights cancer screening in patients with high risk factors and new exam findings in patients with syncopal events having negative initial workup.

Author Affiliations: Department of Internal Medicine, The University of Tennessee Health Science Center, Memphis, Tennessee (Usman, Yahya, Marella, Jain, Peravali, Premkumar, Bradsher)
Corresponding Author: Rana M. Usman, MD, University of Tennessee Health Science Center, 956 Court Ave, Suite H314, Memphis, TN 38163; phone 917.754.3314; email; ORCID ID 0000-0003-0062-1811.
Funding/Support: None declared.
Financial Disclosures: None declared.
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